Nuclear receptors are a class of proteins found within cells that play a key role in regulating gene expression in response to various signals, including hormones, vitamins, and other ligands. They act as transcription factors, binding to specific DNA sequences and influencing the expression of target genes. Nuclear receptors have been implicated in a wide range of biological processes, including metabolism, development, and immune response. Dysregulation of nuclear receptor signaling has been linked to various diseases, such as cancer, metabolic disorders, and autoimmune conditions. Research in the field of nuclear receptors seeks to understand the molecular mechanisms underlying their function and develop potential therapeutic strategies targeting these proteins.